Phoenox Pharma is an early stage biotech company focusing on delivering mitochondrial inhibitors specifically to cancer stem cells for the treatment of orphan oncology indications of significant unmet need. Cancer stem cells (CSCs) are a phenomenon common to all malignancies and drive recurrent disease, metastasis and ultimately death of the cancer patients. While an attractive target, anti-CSC therapeutic agents are not yet on the market and have been limited by toxicity in clinical trials.
Phoenox, through the use of an artificial intelligence platform, is designing novel small molecule prodrugs to deliver payloads targeting multiple facets of mitochondrial respiration and biogenesis. The AI platform will accelerate development by scoring molecules for pharmacokinetic properties based on similarity to known drugs, allowing Phoenox to shorten lead optimization design iterations.
Using artificial intelligence to defeat cancer
Phoenox Pharma is an early stage biotech company focusing on delivering mitochondrial inhibitors specifically to cancer stem cells for the treatment of orphan oncology indications of significant unmet need. Cancer stem cells (CSCs) are a phenomenon common to all malignancies and drive recurrent disease, metastasis and ultimately death of the cancer patients. While an attractive target, anti-CSC therapeutic agents are not yet on the market and have been limited by toxicity in clinical trials.
Phoenox, through the use of an artificial intelligence platform, is designing novel small molecule prodrugs to deliver payloads targeting multiple facets of mitochondrial respiration and biogenesis. The AI platform will accelerate development by scoring molecules for pharmacokinetic properties based on similarity to known drugs, allowing Phoenox to shorten lead optimization design iterations.
Meet the team
Andrew Haller, PhD
Founder and CEO
Naheed Kurji
Collaborator, Board Member
CEO, Cyclica
Ella Korets-Smith
BD Advisor, Board Member
EKS Business Development
Kevin Canning, PhD
Pharma Advisor
VP Strategy, Green Organic Dutchman
Doug Hamilton
Biotech Venture Advisor
CEO, Vasomune
Dr. Steven Gallinger, MD, MSc, FRCSC
Clinical Advisor, Pancreatic Cancer
Head of the HPB Surgical Oncology at UHN and MSH
Dr. George Yousef, MD, PhD, FRCSC (Path), MSc, MBBCh